Anti-CA12 antibody (25-301) (STJ112225)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CA12 (25-301) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CA12 |
| Gene ID | 771 |
| Uniprot ID | CAH12_HUMAN |
| Immunogen Region | 25-301 |
| Immunogen Sequence | APVNGSKWTYFGPDGENSWS KKYPSCGGLLQSPIDLHSDI LQYDASLTPLEFQGYNLSAN KQFLLTNNGHSVKLNLPSDM HIQGLQSRYSATQLHLHWGN PNDPHGSEHTVSGQHFAAEL HIVHYNSDLYPDASTASNKS EGLAVLAVLIEMGSFNPSYD KIFSHLQHVKYKGQEAFVPG FNIEELLPERTAEYYRYRGS LTTPPCNPTVLWTVFRNPVQ ISQEQLLALETALYCTHMD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 25-301 of human CA12 (NP_001209.1). |
Additional Info
| Tissue Specificity | Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis. Expressed in sweat glands and bronchiolar epithelium. |
| Function | Reversible hydration of carbon dioxide. |
| Protein Name | Carbonic Anhydrase 12Carbonate Dehydratase XiiCarbonic Anhydrase XiiCa-XiiTumor Antigen Hom-Rcc-3.1.3 |
| Database Links | Reactome: R-HSA-1475029 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Carbonic Anhydrase 12 antibodyAnti-Carbonate Dehydratase Xii antibodyAnti-Carbonic Anhydrase Xii antibodyAnti-Ca-Xii antibodyAnti-Tumor Antigen Hom-Rcc-3.1.3 antibodyAnti-CA12 antibody |
Information sourced from Uniprot.org