Anti-CA IX antibody [ZR367] (STJ180551)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant human CA9 protein fragment (around aa 314-410) (exact sequence is proprietary)
General Information
| Short Description | Rabbit monoclonal Carbonic Anhydrase 9 antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZR367 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purified |
| Dilution Range | 1:100-200 |
| Formulation | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Target Information
| Gene Symbol | CA9 |
| Gene ID | 768 |
| Uniprot ID | CAH9_HUMAN |
| Immunogen | Recombinant human CA9 protein fragment (around aa 314-410) (exact sequence is proprietary) |
| Specificity | Positive Control: Normal renal tissue |
Additional Info
| Tissue Specificity | Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa. |
| Post Translational Modifications | Asn-346 bears high-mannose type glycan structures. |
| Function | Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). |
| Protein Name | Carbonic Anhydrase 9Carbonate Dehydratase IxCarbonic Anhydrase IxCa-IxCaixMembrane Antigen MnP54/58nRenal Cell Carcinoma-Associated Antigen G250Rcc-Associated Antigen G250Pmw1 |
| Database Links | Reactome: R-HSA-1234158Reactome: R-HSA-1475029 |
| Cellular Localisation | NucleusNucleolusCell MembraneSingle-Pass Type I Membrane ProteinCell ProjectionMicrovillus MembraneFound On The Surface Microvilli And In The NucleusParticularly In Nucleolus |
| Alternative Antibody Names | Anti-Carbonic Anhydrase 9 antibodyAnti-Carbonate Dehydratase Ix antibodyAnti-Carbonic Anhydrase Ix antibodyAnti-Ca-Ix antibodyAnti-Caix antibodyAnti-Membrane Antigen Mn antibodyAnti-P54/58n antibodyAnti-Renal Cell Carcinoma-Associated Antigen G250 antibodyAnti-Rcc-Associated Antigen G250 antibodyAnti-Pmw1 antibodyAnti-CA9 antibodyAnti-G250 antibodyAnti-MN antibody |
Information sourced from Uniprot.org