• Western blot analysis of extracts of various cell lines, using C8B antibody (STJ110622) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Western blot analysis of extracts of various cell lines, using C8B antibody (STJ110622) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-C8B antibody (55-350) (STJ110622)

SKU:
STJ110622

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-C8B (55-350) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: C8B
Gene ID: 732
Uniprot ID: CO8B_HUMAN
Immunogen Region: 55-350
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 55-350 of human C8B (NP_000057.2).
Immunogen Sequence: SVDVTLMPIDCELSSWSSWT TCDPCQKKRYRYAYLLQPSQ FHGEPCNFSDKEVEDCVTNR PCRSQVRCEGFVCAQTGRCV NRRLLCNGDNDCGDQSDEAN CRRIYKKCQHEMDQYWGIGS LASGINLFTNSFEGPVLDHR YYAGGCSPHYILNTRFRKPY NVESYTPQTQGKYEFILKEY ESYSDFERNVTEKMASKSGF SFGFKIPGIFELGISSQSDR GKHYIRRTKRFSHTKSVFL
Post Translational Modifications N-glycosylated.contains one or two bound glycans. Not O-glycosylated.
Function Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
Protein Name Complement Component C8 Beta Chain
Complement Component 8 Subunit Beta
Database Links Reactome: R-HSA-166665
Reactome: R-HSA-977606
Cellular Localisation Secreted
Alternative Antibody Names Anti-Complement Component C8 Beta Chain antibody
Anti-Complement Component 8 Subunit Beta antibody
Anti-C8B antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance