Anti-C7orf50 antibody (1-194) (STJ116694)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal C7orf50 (1-194) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CHLSN |
| Gene ID | 84310 |
| Uniprot ID | CHOLN_HUMAN |
| Immunogen Region | 1-194 |
| Immunogen Sequence | MAKQKRKVPEVTEKKNKKLK KASAEGPLLGPEAAPSGEGA GSKGEAVLRPGLDAEPELSP EEQRVLERKLKKERKKEERQ RLREAGLVAQHPPARRSGAE LALDYLCRWAQKHKNWRFQK TRQTWLLLHMYDSDKVPDEH FSTLLAYLEGLQGRARELTV QKAEALMRELDEEGSDPPLP GRAQRIRQVLQLLS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human C7orf50 (NP_115726.1). |
Additional Info
| Tissue Specificity | Secreted from the instestine, secretion is induced by feeding and cholesterol absorption. |
| Function | Hormone secreted from the intestine in response to cholesterol, where it acts to inhibit cholesterol synthesis in the liver and VLDL secretion,leading to a reduction in circulating cholesterol levels. Acts through binding to its receptor, GPR146. |
| Protein Name | Protein Cholesin |
| Database Links | |
| Cellular Localisation | SecretedSecreted Via ExosomesSecretion Is Induced By Feeding And Cholesterol Absorption |
| Alternative Antibody Names | Anti-Protein Cholesin antibodyAnti-CHLSN antibodyAnti-C7orf50 antibodyAnti-FP15621 antibody |
Information sourced from Uniprot.org