| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-C6 (586-934) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
C6 |
| Gene ID: |
729 |
| Uniprot ID: |
CO6_HUMAN |
| Immunogen Region: |
586-934 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 586-934 of human C6 (NP_000056.2). |
| Immunogen Sequence: |
TRECNNPAPQRGGKRCEGEK RQEEDCTFSIMENNGQPCIN DDEEMKEVDLPEIEADSGCP QPVPPENGFIRNEKQLYLVG EDVEISCLTGFETVGYQYFR CLPDGTWRQGDVECQRTECI KPVVQEVLTITPFQRLYRIG ESIELTCPKGFVVAGPSRYT CQGNSWTPPISNSLTCEKDT LTKLKGHCQLGQKQSGSECI CMSPEEDCSHHSEDLCVFDT DSNDYFTSPACKFLAEKCL |
| Post Translational Modifications | All cysteine residues are assumed to be cross-linked to one another. Individual modules containing an even number of conserved cysteine residues are supposed to have disulfide linkages only within the same module. |
| Function | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. |
| Protein Name | Complement Component C6 |
| Database Links | Reactome: R-HSA-166665Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Complement Component C6 antibodyAnti-C6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
