Anti-C5AR1 antibody (STJ11107780)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit polyclonal C5a Anaphylatoxin Chemotactic Receptor 1 antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB, 1:500-1:1000IHC-P, 1:50-1:200ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide 50% Glycerol pH7.3 |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | C5AR1 |
| Gene ID | 728 |
| Uniprot ID | C5AR1_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Immunogen Sequence | Human |
Additional Info
| Function | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. |
| Protein Name | C5a Anaphylatoxin Chemotactic Receptor 1C5a Anaphylatoxin Chemotactic ReceptorC5a-RC5arCd Antigen Cd88 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594Reactome: R-HSA-6798695Reactome: R-HSA-977606 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmic VesiclePhosphorylated C5ar Colocalizes With Arrb1 And Arrb2 In Cytoplasmic Vesicles |
| Alternative Antibody Names | Anti-C5a Anaphylatoxin Chemotactic Receptor 1 antibodyAnti-C5a Anaphylatoxin Chemotactic Receptor antibodyAnti-C5a-R antibodyAnti-C5ar antibodyAnti-Cd Antigen Cd88 antibodyAnti-C5AR1 antibodyAnti-C5AR antibodyAnti-C5R1 antibody |
Information sourced from Uniprot.org