Anti-C3aR antibody [HC3aRZ8] (STJ16103157)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2b
ImmunogenHuman C3aR transfectants
General Information
| Short Description | Mouse monoclonal anti-C3aR for use in FC and IHC-F in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IHC-F |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | HC3aRZ8 |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by protein-A affinity chromatography. |
| Formulation | Phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | C3AR1 |
| Gene ID | 719 |
| Uniprot ID | C3AR_HUMAN |
| Immunogen | Human C3aR transfectants |
Additional Info
| Post Translational Modifications | Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin. O-glycosylated. |
| Function | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. |
| Protein Name | C3a Anaphylatoxin Chemotactic ReceptorC3arC3a-R |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594Reactome: R-HSA-6798695Reactome: R-HSA-9660826Reactome: R-HSA-977606 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C3a Anaphylatoxin Chemotactic Receptor antibodyAnti-C3ar antibodyAnti-C3a-R antibodyAnti-C3AR1 antibodyAnti-AZ3B antibodyAnti-C3R1 antibodyAnti-HNFAG09 antibody |
Information sourced from Uniprot.org