| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-C2 domain-containing protein 5 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | C2CD5 |
| Gene ID: | 9847 |
| Uniprot ID: | C2CD5_HUMAN |
| Specificity: | This antibody detects endogenous levels of KIAA0528 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human KIAA0528 |
| Function | Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM. |
| Protein Name | C2 Domain-Containing Protein 5C2 Domain-Containing Phosphoprotein Of 138 Kda |
| Database Links | Reactome: R-HSA-1445148 |
| Cellular Localisation | Cytoplasmic Vesicle MembraneCytoplasmCell CortexCell MembraneCell ProjectionRuffleDynamically Associated With Glut4-Containing Glucose Storage Vesicles (Gsv) And Plasma Membrane In Response To Insulin Stimulation |
| Alternative Antibody Names | Anti-C2 Domain-Containing Protein 5 antibodyAnti-C2 Domain-Containing Phosphoprotein Of 138 Kda antibodyAnti-C2CD5 antibodyAnti-CDP138 antibodyAnti-KIAA0528 antibody |
Information sourced from Uniprot.org