• Western blot analysis of various lysates using C2CD5 Rabbit polyclonal antibody (STJ116569) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-C2CD5 antibody (732-1051) (STJ116569)

SKU:
STJ116569

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-C2CD5 (732-1051) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: C2CD5
Gene ID: 9847
Uniprot ID: C2CD5_HUMAN
Immunogen Region: 732-1051
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 732-1051 of human C2CD5 (NP_001273103.1).
Immunogen Sequence: RLSSLNLTNQALNKNFNDLC ENLLKSLYFKLRSMIPCCLC HVNFTVSLPEDELIQVTVTA VAITFDKNQALQTTKTPVEK SLQRASTDNEELLQFPLELC SDSLPSHPFPPAKEHLESAS SNSGIPAAQRATSVDYSSFA DRCSSWIELIKLKAQTIRRG SIKTTMTVEKASPVGDGNFR NRSAPPCANSTVGVVKMTPL SFIPGAKITKYLGIINMFFI RETTSLREEGGVSGFLHAF
Post Translational Modifications Phosphorylated on Ser-197 by active myristoylated kinase AKT2.insulin-stimulated phosphorylation by AKT2 regulates SLC2A4/GLUT4 translocation into the plasma membrane.
Function Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM.
Protein Name C2 Domain-Containing Protein 5
C2 Domain-Containing Phosphoprotein Of 138 Kda
Database Links Reactome: R-HSA-1445148
Cellular Localisation Cytoplasmic Vesicle Membrane
Cytoplasm
Cell Cortex
Cell Membrane
Cell Projection
Ruffle
Dynamically Associated With Glut4-Containing Glucose Storage Vesicles (Gsv) And Plasma Membrane In Response To Insulin Stimulation
Alternative Antibody Names Anti-C2 Domain-Containing Protein 5 antibody
Anti-C2 Domain-Containing Phosphoprotein Of 138 Kda antibody
Anti-C2CD5 antibody
Anti-CDP138 antibody
Anti-KIAA0528 antibody

Information sourced from Uniprot.org

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