Anti-C14orf166 antibody [ZN182] (STJA0033356)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenFull length human recombinant protein of human C14orf166 (NP_057123) produced in E.coli.
STJA0033356
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General Information

Short DescriptionMouse monoclonal anti-C14orf166 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC-P
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDZN182
IsotypeIgG1
ConjugationUnconjugated
Concentration0.5-1.0 mg/mL
PurificationAffinity Chromatography
Dilution RangeIHC 1:50-1:100
FormulationPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage InstructionStore at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.

Target Information

Gene SymbolRTRAF
Gene ID51637
Uniprot IDRTRAF_HUMAN
ImmunogenFull length human recombinant protein of human C14orf166 (NP_057123) produced in E.coli.

Additional Info

Function RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. Component of the tRNA-splicing ligase complex and is required for tRNA ligation. May be required for RNA transport. (Microbial infection) In case of infection by influenza virus A (IVA), is involved in viral replication.
Protein Name Rna Transcription - Translation And Transport Factor Protein
Cle7 Homolog
Cle
Hcle
Database Links Reactome: R-HSA-6784531
Cellular Localisation Nucleus
Cytoplasm
Cytosol
Perinuclear Region
Cytoskeleton
Microtubule Organizing Center
Centrosome
May Localize At The Centrosome During Mitosis
Shuttles Between The Cytosol And The Nucleus: Enters Into The Nucleus In Case Of Active Transcription While It Accumulates In Cytosol When Transcription Level Is Low
(Microbial Infection) Following Influenza A Virus (Iav) Infection
Included In Influenza A Virions Via Its Association With Packaged Viral Ribonucleoproteins (Vrnp) In The Nucleus And Cytoplasm
Alternative Antibody Names Anti-Rna Transcription - Translation And Transport Factor Protein antibody
Anti-Cle7 Homolog antibody
Anti-Cle antibody
Anti-Hcle antibody
Anti-RTRAF antibody
Anti-C14orf166 antibody
Anti-CGI-99 antibody

Information sourced from Uniprot.org

Citations

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