Anti-c-Myb antibody (281-294) (STJ71218)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-c-Myb (281-294) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 70kDa band observed in lysates of cell line MOLT4 and in preliminary testing of Human Bone Marrow and Lymph Node lysate (calculated MW of 72.3kDa according to NP_005366.2). Recom |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | MYB |
| Gene ID | 4602 |
| Uniprot ID | MYB_HUMAN |
| Accession Number | NP_001123645.1; NP_005366.2; NP_001123644.1; NP_001155128.1; NP_001155129.1; NP_001155130.1; NP_001155131.1 |
| Immunogen Region | 281-294 |
| Immunogen Sequence | QRHYNDEDPEKEKR |
| Specificity | This antibody is expected to recognize isoforms 1-7 only (Numbering from NCBI RefSeq). (NP_001123645.1; NP_005366.2; NP_001123644.1; NP_001155128.1; NP_001155129.1; NP_001155130.1; NP_001155131.1) |
Additional Info
| Function | Transcriptional activator.DNA-binding protein that specifically recognize the sequence 5'-YAACGTG-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. |
| Protein Name | Transcriptional Activator MybProto-Oncogene C-Myb |
| Database Links | Reactome: R-HSA-8939236Reactome: R-HSA-9018519Reactome: R-HSA-9616222Reactome: R-HSA-983231Reactome: R-HSA-9834899 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcriptional Activator Myb antibodyAnti-Proto-Oncogene C-Myb antibodyAnti-MYB antibody |
Information sourced from Uniprot.org