Anti-c-MET (Hepatocyte Growth Factor Receptor) antibody [3D4] (STJ16101402)

Anti-c-MET (Hepatocyte Growth Factor Receptor) antibody [3D4] (STJ16101402)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIG2a
ImmunogenSynthetic peptide derived from cytoplasmic domain of human c-Met protein
STJ16101402-05
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General Information

Short DescriptionMouse monoclonal anti-c-MET (Hepatocyte Growth Factor Receptor) for use in IHC-P, ICC and IF in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC-P/ICC/IF
HostMouse
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone ID3D4
IsotypeIG2a
ConjugationUnconjugated
Dilution RangeIHC-P
ICC
IF 1:250
FormulationPBS with 1% BSA and 0.1% sodium azide
Storage InstructionStore at 2-8°C for up to 1-year, upon receipt.

Target Information

ImmunogenSynthetic peptide derived from cytoplasmic domain of human c-Met protein

Additional Info

Background MET is a tyrosine kinase receptor for the hepatocyte growth factor. It is linked to functions such as cell proliferation, scattering, morphogenesis, and survival. Ligand binding at the cell surface induces autophosphorylation of MET that provides docking sites for downstream signaling molecules. After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3.

Information sourced from Uniprot.org

Citations

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