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| Short Description : | Mouse monoclonal anti-C-erbB-2 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-P |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | CB11 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Dilution Range: | IHC 1:40 |
| Formulation: | Tissue culture supernatant with sodium azide |
| Storage Instruction: | Store at 2-8°C for up to 1-year, upon receipt. |
| Immunogen: | Synthetic peptide corresponding to a site on the internal domain of the human c-erbB-2 oncoprotein. |
| Background | The c-erbB-2 oncoprotein is closely related in structure to the epidermal growth factor receptor and is a member of a large family of cell surface growth factor receptors. c-erbB-2 oncoprotein is reported to be detectable in a proportion of breast and other adenocarcinomas as well as transitional cell carcinomas. c-erbB-2 oncoprotein is present in a wide variety of cell types in a range of normal human fetal and adult tissues, including breast, stomach and ovary. CB11 detects the internal domain of the c-erbB-2 oncoprotein. |
Information sourced from Uniprot.org
