Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-C-erbB-2 is suitable for use in Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | CB11 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Tissue culture supernatant with sodium azide |
Dilution Range: | IHC 1:40 |
Storage Instruction: | Store at 2-8°C upon receipt. |
Immunogen: | Synthetic peptide corresponding to a site on the internal domain of the human c-erbB-2 oncoprotein. |
Background | The c-erbB-2 oncoprotein is closely related in structure to the epidermal growth factor receptor and is a member of a large family of cell surface growth factor receptors. c-erbB-2 oncoprotein is reported to be detectable in a proportion of breast and other adenocarcinomas as well as transitional cell carcinomas. c-erbB-2 oncoprotein is present in a wide variety of cell types in a range of normal human fetal and adult tissues, including breast, stomach and ovary. CB11 detects the internal domain of the c-erbB-2 oncoprotein. |
Information sourced from Uniprot.org