Anti-BTBD8 antibody (224-274 aa) (STJ197736)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human BTBD8 at the amino acid range 224-274
General Information
| Short Description | Rabbit polyclonal anti-BTB/POZ domain-containing protein 8 (224-274 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BTBD8 |
| Gene ID | 284697 |
| Uniprot ID | BTBD8_HUMAN |
| Immunogen | Synthesized peptide derived from the human BTBD8 at the amino acid range 224-274 |
| Immunogen Region | 224-274 aa |
| Specificity | This antibody detects endogenous levels of human BTBD8 |
Additional Info
| Function | Involved in clathrin-mediated endocytosis at the synapse. Plays a role in neuronal development and in synaptic vesicle recycling in mature neurons, a process required for normal synaptic transmission. |
| Protein Name | Btb/Poz Domain-Containing Protein 8Ap2-Interacting Clathrin-EndocytosisApache |
| Database Links | |
| Cellular Localisation | Cell ProjectionAxonPresynapseCytoplasmic VesicleClathrin-Coated VesicleNucleusIn Primary CulturesMainly Present At Axonal And Presynaptic Terminal Levels Of Mature NeuronsIn Immature NeuronsLocalizes To The Cell Body And Growing ProcessesIncluding AxonsLocalized To Nucleus In Fetal Cells |
| Alternative Antibody Names | Anti-Btb/Poz Domain-Containing Protein 8 antibodyAnti-Ap2-Interacting Clathrin-Endocytosis antibodyAnti-Apache antibodyAnti-BTBD8 antibodyAnti-KIAA1107 antibody |
Information sourced from Uniprot.org