Anti-BTBD1 antibody (115-165 aa) (STJ194467)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human BTBD1 at the amino acid range 115-165
General Information
| Short Description | Rabbit polyclonal anti-BTB/POZ domain-containing protein 1 (115-165 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BTBD1 |
| Gene ID | 53339 |
| Uniprot ID | BTBD1_HUMAN |
| Immunogen | Synthesized peptide derived from the human BTBD1 at the amino acid range 115-165 |
| Immunogen Region | 115-165 aa |
| Specificity | This antibody detects endogenous levels of BTBD1 at Human/Mouse |
Additional Info
| Function | Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to regulate expression levels and/or subnuclear distribution of TOP1, via an unknown mechanism. May play a role in mesenchymal differentiation where it promotes myogenic differentiation and suppresses adipogenesis. |
| Protein Name | Btb/Poz Domain-Containing Protein 1Hepatitis C Virus Ns5a-Transactivated Protein 8Hcv Ns5a-Transactivated Protein 8 |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmLocalizes To Punctate Or Elongated Cytoplasmic Bodies |
| Alternative Antibody Names | Anti-Btb/Poz Domain-Containing Protein 1 antibodyAnti-Hepatitis C Virus Ns5a-Transactivated Protein 8 antibodyAnti-Hcv Ns5a-Transactivated Protein 8 antibodyAnti-BTBD1 antibodyAnti-C15orf1 antibodyAnti-NS5ATP8 antibody |
Information sourced from Uniprot.org