| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-BRO1 domain-containing protein BROX is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
BROX |
| Gene ID: |
148362 |
| Uniprot ID: |
BROX_HUMAN |
| Specificity: |
This antibody detects endogenous levels of C1orf58 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human C1orf58 |
| Function | Nuclear envelope-associated factor that is involved in the nuclear envelope ruptures during interphase (NERDI) repair, where it is locally recruited by CHMP5 and reduces cytoskeletal stress through its action on SYN2 to help reseal the ruptured membrane. |
| Protein Name | Bro1 Domain-Containing Protein BroxBro1 Domain- And Caax Motif-Containing Protein |
| Cellular Localisation | Nucleus MembraneLipid-AnchorDuring Nuclear Envelope RepairLocalizes At Rupture Sites Where It Is Recruited By The Chmp7/Escrt-Iii Axis |
| Alternative Antibody Names | Anti-Bro1 Domain-Containing Protein Brox antibodyAnti-Bro1 Domain- And Caax Motif-Containing Protein antibodyAnti-BROX antibodyAnti-BROFTI antibodyAnti-C1orf58 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
