Anti-BRK1 antibody (1-75) (STJ119333)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal BRK1 (1-75) antibody for use in IHC-P, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BRK1 |
| Gene ID | 55845 |
| Uniprot ID | BRK1_HUMAN |
| Immunogen Region | 1-75 |
| Immunogen Sequence | MAGQEDPVQREIHQDWANRE YIEIITSSIKKIADFLNSFD MSCRSRLATLNEKLTALERR IEYIEARVTKGETLT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human BRK1 (NP_060932.2). |
Additional Info
| Function | Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes. |
| Protein Name | Protein Brick1Brk1 |
| Database Links | Reactome: R-HSA-2029482Reactome: R-HSA-4420097Reactome: R-HSA-5663213Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013423Reactome: R-HSA-9664422 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Protein Brick1 antibodyAnti-Brk1 antibodyAnti-BRK1 antibodyAnti-C3orf10 antibodyAnti-HSPC300 antibodyAnti-MDS027 antibody |
Information sourced from Uniprot.org