Anti-BRaf-V600A Mutant antibody (STJA0033566)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
ImmunogenA synthetic peptide from the internal region of BRAF which includes the mutation of V600A, human origin.
General Information
| Short Description | Mouse monoclonal anti-BRaf-V600A Mutant for use in WB, ICC, IF and ELISA in Vertebrates samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF/ELISA |
| Host | Mouse |
| Reactivity | Vertebrates |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Purification | Purified from ascites |
| Dilution Range | ELISA-1:1000-1:5000WB-1:500-1:1000ICC/IF-1:50-1:100IHC-P-1:25-1:100 |
| Formulation | Liquid in PBS (without Mg2+ and Ca2+) , pH 7.4, 150 mM NaCl, 50% glycerol |
| Storage Instruction | Store at-20°C. Avoid freeze/thaw cycles. |
Target Information
| Immunogen | A synthetic peptide from the internal region of BRAF which includes the mutation of V600A, human origin. |
Additional Info
| Background | BRAF belongs to a family of serine-threonine protein kinases. As a part of a signaling pathway known as the the RAS/MAPK pathway, it plays an important part in many cellular processes. The processes include cell proliferation, differentiation and transcriptional regulation. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF cause cardiofaciocutaneous syndrome. Acquired mutations in BRAF have been found in cancers. |
Information sourced from Uniprot.org