Anti-Brachyury antibody (235-435aa) [ZR391] (STJ180550)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant fragment (around aa 235-435) of human TBXT protein
General Information
| Short Description | Rabbit monoclonal Brachyury (235-435aa) antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ZR391 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purified |
| Dilution Range | 1:100-200 |
| Formulation | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Target Information
| Gene Symbol | TBXT |
| Gene ID | 6862 |
| Uniprot ID | TBXT_HUMAN |
| Immunogen | Recombinant fragment (around aa 235-435) of human TBXT protein |
| Immunogen Region | 235-435aa |
| Specificity | Positive Control: Chordoma |
Additional Info
| Tissue Specificity | Detected in testis, but not in other, normal tissues. Detected in lung tumors (at protein level). |
| Function | Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence and activates gene transcription when bound to such a site. |
| Protein Name | T-Box Transcription Factor TBrachyury ProteinProtein T |
| Database Links | Reactome: R-HSA-9733709Reactome: R-HSA-9754189Reactome: R-HSA-9758919Reactome: R-HSA-9793380Reactome: R-HSA-9796292Reactome: R-HSA-9823730 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-T-Box Transcription Factor T antibodyAnti-Brachyury Protein antibodyAnti-Protein T antibodyAnti-TBXT antibodyAnti-T antibody |
Information sourced from Uniprot.org