Anti-BPNT2 antibody (STJA0008764)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human IMPAD1
General Information
| Short Description | Rabbit polyclonal anti-Golgi-resident adenosine 3 NA, 5 bisphosphate 3 phosphatase, 5 bisphosphate nucleotidase 2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BPNT2 |
| Gene ID | 54928 |
| Uniprot ID | IMPA3_HUMAN |
| Immunogen | Synthesized peptide derived from human IMPAD1 |
| Specificity | This antibody detects endogenous levels of IMPAD1 at Human, Mouse, Rat |
Additional Info
| Function | Exhibits 3'-nucleotidase activity toward adenosine 3',5'-bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1,4)P2, I(1,3,4)P3, I(1,4,5)P3 and I(1,3,4,5)P4. |
| Protein Name | Golgi-Resident Adenosine 3' -5'-Bisphosphate 3'-PhosphataseGolgi-Resident Pap PhosphataseGpapp3'(2' - 5'-Bisphosphate Nucleotidase 2Inositol Monophosphatase Domain-Containing Protein 1Myo-Inositol Monophosphatase A3Phosphoadenosine Phosphate 3'-Nucleotidase |
| Database Links | Reactome: R-HSA-156584 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembraneSingle-Pass Type Ii Membrane ProteinThe Catalytic Core Is Predicted To Reside Within The Golgi Lumen |
| Alternative Antibody Names | Anti-Golgi-Resident Adenosine 3' -5'-Bisphosphate 3'-Phosphatase antibodyAnti-Golgi-Resident Pap Phosphatase antibodyAnti-Gpapp antibodyAnti-3'(2' - 5'-Bisphosphate Nucleotidase 2 antibodyAnti-Inositol Monophosphatase Domain-Containing Protein 1 antibodyAnti-Myo-Inositol Monophosphatase A3 antibodyAnti-Phosphoadenosine Phosphate 3'-Nucleotidase antibodyAnti-BPNT2 antibodyAnti-IMPA3 antibodyAnti-IMPAD1 antibody |
Information sourced from Uniprot.org