Anti-BPNT1 antibody (STJA0009689)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human BPNT1
General Information
| Short Description | Rabbit polyclonal anti-3 2 NA, 5 bisphosphate nucleotidase 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BPNT1 |
| Gene ID | 10380 |
| Uniprot ID | BPNT1_HUMAN |
| Immunogen | Synthesized peptide derived from human BPNT1 |
| Specificity | This antibody detects endogenous levels of BPNT1 at Human, Mouse, Rat |
Additional Info
| Function | Phosphatase that converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP and inositol 1,4-bisphosphate (Ins(1,4)P2) to inositol 4-phosphate. Is also able to hydrolyze adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS). Probably prevents the toxic accumulation of PAP, a compound which inhibits a variety of proteins, including PAPS-utilizing enzymes such as sulfotransferases, and RNA processing enzymes. Could also play a role in inositol recycling and phosphoinositide metabolism. Is not active on 3'-AMP, inositol-1-phosphate and inositol-1,4,5-triphosphate. |
| Protein Name | 3'(2' -5'-Bisphosphate Nucleotidase 13'-Phosphoadenosine 5'-Phosphate PhosphatasePap PhosphataseBisphosphate 3'-Nucleotidase 1Bpntase 1HspipInositol-Polyphosphate 1-Phosphatase |
| Database Links | Reactome: R-HSA-156584 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-3'(2' -5'-Bisphosphate Nucleotidase 1 antibodyAnti-3'-Phosphoadenosine 5'-Phosphate Phosphatase antibodyAnti-Pap Phosphatase antibodyAnti-Bisphosphate 3'-Nucleotidase 1 antibodyAnti-Bpntase 1 antibodyAnti-Hspip antibodyAnti-Inositol-Polyphosphate 1-Phosphatase antibodyAnti-BPNT1 antibody |
Information sourced from Uniprot.org