Anti-BPIFA1 antibody (Internal) (STJ95164)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the Internal region of human PLUNC.
General Information
| Short Description | Rabbit polyclonal anti-BPI fold-containing family A member 1 (Internal) for use in IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BPIFA1 |
| Gene ID | 51297 |
| Uniprot ID | BPIA1_HUMAN |
| Immunogen | Synthesized peptide derived from the Internal region of human PLUNC. |
| Immunogen Region | Internal |
| Specificity | PLUNC Polyclonal Antibody detects endogenous levels of PLUNC protein. |
Additional Info
| Post Translational Modifications | May be N-glycosylated. |
| Function | Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants. May attract macrophages and neutrophils. |
| Protein Name | Bpi Fold-Containing Family A Member 1Lung-Specific Protein XNasopharyngeal Carcinoma-Related ProteinPalate Lung And Nasal Epithelium Clone ProteinSecretory Protein In Upper Respiratory TractsShort Plunc1Splunc1Tracheal Epithelium-Enriched ProteinVon Ebner Protein Hl |
| Database Links | Reactome: R-HSA-6803157 |
| Cellular Localisation | SecretedApical Side Of Airway Epithelial CellsDetected In Airway Surface LiquidNasal Mucus And Sputum |
| Alternative Antibody Names | Anti-Bpi Fold-Containing Family A Member 1 antibodyAnti-Lung-Specific Protein X antibodyAnti-Nasopharyngeal Carcinoma-Related Protein antibodyAnti-Palate Lung And Nasal Epithelium Clone Protein antibodyAnti-Secretory Protein In Upper Respiratory Tracts antibodyAnti-Short Plunc1 antibodyAnti-Splunc1 antibodyAnti-Tracheal Epithelium-Enriched Protein antibodyAnti-Von Ebner Protein Hl antibodyAnti-BPIFA1 antibodyAnti-LUNX antibodyAnti-NASG antibodyAnti-PLUNC antibodyAnti-SPLUNC1 antibodyAnti-SPURT antibodyAnti-UNQ787 antibodyAnti-PRO1606 antibody |
Information sourced from Uniprot.org