Anti-BPGM antibody (1-259aa) [AT2E11] (STJA0041829)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenRecombinant human BPGM (1-259aa) purified from E. coli.
General Information
| Short Description | Mouse monoclonal anti-BPGM (1-259aa) for use in ELISA, WB, ICC, IF and FACS in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF/FACS |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT2E11 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BPGM |
| Gene ID | 669 |
| Uniprot ID | PMGE_HUMAN |
| Accession Number | NP_001715 |
| Immunogen | Recombinant human BPGM (1-259aa) purified from E. coli. |
| Immunogen Region | 1-259aa |
Additional Info
| Tissue Specificity | Expressed in red blood cells. Expressed in non-erythroid cells of the placenta.present in the syncytiotrophoblast layer of the placental villi at the feto-maternal interface (at protein level). |
| Post Translational Modifications | Glycation of Lys-159 in diabetic patients inactivates the enzyme. |
| Function | Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase activity. |
| Protein Name | Bisphosphoglycerate MutaseBpgm2 -3-Bisphosphoglycerate Mutase - Erythrocyte2 -3-Bisphosphoglycerate Synthase2 -3-Diphosphoglycerate MutaseDpgmBpg-Dependent Pgam |
| Database Links | Reactome: R-HSA-70171 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Bisphosphoglycerate Mutase antibodyAnti-Bpgm antibodyAnti-2 -3-Bisphosphoglycerate Mutase - Erythrocyte antibodyAnti-2 -3-Bisphosphoglycerate Synthase antibodyAnti-2 -3-Diphosphoglycerate Mutase antibodyAnti-Dpgm antibodyAnti-Bpg-Dependent Pgam antibodyAnti-BPGM antibody |
Information sourced from Uniprot.org