Anti-BPGM antibody (1-259) (STJ110190)

Name: Anti-BPGM antibody (1-259) (STJ110190)
SKU: STJ110190
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ110190

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Short Description	Rabbit polyclonal BPGM (1-259) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	BPGM
Gene ID	669
Uniprot ID	PMGE_HUMAN
Immunogen Region	1-259
Immunogen Sequence	MSKYKLIMLRHGEGAWNKEN RFCSWVDQKLNSEGMEEARN CGKQLKALNFEFDLVFTSVL NRSIHTAWLILEELGQEWVP VESSWRLNERHYGALIGLNR EQMALNHGEEQVRLWRRSYN VTPPPIEESHPYYQEIYNDR RYKVCDVPLDQLPRSESLKD VLERLLPYWNERIAPEVLRG KTILISAHGNSSRALLKHLE GISDEDIINITLPTGVPILL ELDENLRAVGPHQFLGDQE
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-259 of human BPGM (NP_001715.1).

Tissue Specificity	Expressed in red blood cells. Expressed in non-erythroid cells of the placenta.present in the syncytiotrophoblast layer of the placental villi at the feto-maternal interface (at protein level).
Post Translational Modifications	Glycation of Lys-159 in diabetic patients inactivates the enzyme.
Function	Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase activity.
Protein Name	Bisphosphoglycerate Mutase Bpgm 2 -3-Bisphosphoglycerate Mutase - Erythrocyte 2 -3-Bisphosphoglycerate Synthase 2 -3-Diphosphoglycerate Mutase Dpgm Bpg-Dependent Pgam
Database Links	Reactome: R-HSA-70171
Cellular Localisation
Alternative Antibody Names	Anti-Bisphosphoglycerate Mutase antibody Anti-Bpgm antibody Anti-2 -3-Bisphosphoglycerate Mutase - Erythrocyte antibody Anti-2 -3-Bisphosphoglycerate Synthase antibody Anti-2 -3-Diphosphoglycerate Mutase antibody Anti-Dpgm antibody Anti-Bpg-Dependent Pgam antibody Anti-BPGM antibody

Information sourced from Uniprot.org