Anti-BNC1 antibody (10-90 aa) (STJ190206)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 10-90
General Information
| Short Description | Rabbit polyclonal anti-Zinc finger protein basonuclin-1 (10-90 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BNC1 |
| Gene ID | 646 |
| Uniprot ID | BNC1_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 10-90 |
| Immunogen Region | 10-90 aa |
| Specificity | BNC1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Phosphorylation on Ser-537 and Ser-541 leads to cytoplasmic localization. |
| Function | Transcriptional activator. It is likely involved in the regulation of keratinocytes terminal differentiation in squamous epithelia and hair follicles. Required for the maintenance of spermatogenesis. It is involved in the positive regulation of oocyte maturation, probably acting through the control of BMP15 levels and regulation of AKT signaling cascade. May also play a role in the early development of embryos. |
| Protein Name | Zinc Finger Protein Basonuclin-1 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmNucleoplasmRelocates To The Midpiece Of The Flagellum During Late Spermiogenesis In Spermatids |
| Alternative Antibody Names | Anti-Zinc Finger Protein Basonuclin-1 antibodyAnti-BNC1 antibodyAnti-BNC antibody |
Information sourced from Uniprot.org