• STJ73311 (1µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-BMPR2 antibody (Internal) (STJ73311)

SKU:
STJ73311-100

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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Rat/Dog/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-BMPR2 (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-1-3µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: BMPR2
Gene ID: 659
Uniprot ID: BMPR2_HUMAN
Immunogen Region: Internal
Accession Number: NP_001195.2
Immunogen Sequence: DLETNKLDPKEVDK
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
Protein Name Bone Morphogenetic Protein Receptor Type-2
Bmp Type-2 Receptor
Bmpr-2
Bone Morphogenetic Protein Receptor Type Ii
Bmp Type Ii Receptor
Bmpr-Ii
Database Links Reactome: R-HSA-201451
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Bone Morphogenetic Protein Receptor Type-2 antibody
Anti-Bmp Type-2 Receptor antibody
Anti-Bmpr-2 antibody
Anti-Bone Morphogenetic Protein Receptor Type Ii antibody
Anti-Bmp Type Ii Receptor antibody
Anti-Bmpr-Ii antibody
Anti-BMPR2 antibody
Anti-PPH1 antibody

Information sourced from Uniprot.org

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