| Host: |
Rabbit |
| Applications: |
IHC/IF/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Bone morphogenetic protein receptor type-1B (21-70 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC-P 1:50-200ELISA 1:10000-20000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
BMPR1B |
| Gene ID: |
658 |
| Uniprot ID: |
BMR1B_HUMAN |
| Immunogen Region: |
21-70 aa |
| Specificity: |
The antibody detects endogenous BMPR-IB |
| Immunogen: |
Synthetic peptide from the human protein at the amino acid range 21-70 |
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction. |
| Protein Name | Bone Morphogenetic Protein Receptor Type-1bBmp Type-1b ReceptorBmpr-1bCd Antigen Cdw293 |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Bone Morphogenetic Protein Receptor Type-1b antibodyAnti-Bmp Type-1b Receptor antibodyAnti-Bmpr-1b antibodyAnti-Cd Antigen Cdw293 antibodyAnti-BMPR1B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
