• Western blot with Anti-BMPR1A Antibody (STJ500279) of mouse skeletal muscle at 1:250 dilution in buffer.

Anti-BMPR1A antibody (460-510) (STJ500279)

SKU:
STJ500279-100

£441.50
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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BMPR1A (460-510) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5 µg/µl
Dilution Range: WB: 1:500
ELISA: 1:10, 000
IP: 1:150
IHC: 1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: BMPR1A
Gene ID: 657
Uniprot ID: BMR1A_HUMAN
Immunogen Region: 460-510
Immunogen: Synthetic peptide taken within amino acid region 460-510 on human Bone morphogenetic protein receptor type-1A.
Tissue Specificity Highly expressed in skeletal muscle.
Post Translational Modifications Glycosylated.
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. May promote the expression of HAMP, potentially via its interaction with BMP2.
Protein Name Bone Morphogenetic Protein Receptor Type-1a
Bmp Type-1a Receptor
Bmpr-1a
Activin Receptor-Like Kinase 3
Alk-3
Serine/Threonine-Protein Kinase Receptor R5
Skr5
Cd Antigen Cd292
Database Links Reactome: R-HSA-201451
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Surface
Alternative Antibody Names Anti-Bone Morphogenetic Protein Receptor Type-1a antibody
Anti-Bmp Type-1a Receptor antibody
Anti-Bmpr-1a antibody
Anti-Activin Receptor-Like Kinase 3 antibody
Anti-Alk-3 antibody
Anti-Serine/Threonine-Protein Kinase Receptor R5 antibody
Anti-Skr5 antibody
Anti-Cd Antigen Cd292 antibody
Anti-BMPR1A antibody
Anti-ACVRLK3 antibody
Anti-ALK3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance