• Immunohistochemistry analysis of paraffin-embedded human stomach using BLVRB antibody (STJ29401) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human liver cancer using BLVRB antibody (STJ29401) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of extracts of various cell lines, using BLVRB Rabbit polyclonal antibody (STJ29401) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-BLVRB antibody (1-206) (STJ29401)

SKU:
STJ29401

£169.50 - £449.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BLVRB (1-206) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:100
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BLVRB
Gene ID: 645
Uniprot ID: BLVRB_HUMAN
Immunogen Region: 1-206
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-206 of human BLVRB (NP_000704.1).
Immunogen Sequence: MAVKKIAIFGATGQTGLTTL AQAVQAGYEVTVLVRDSSRL PSEGPRPAHVVVGDVLQAAD VDKTVAGQDAVIVLLGTRND LSPTTVMSEGARNIVAAMKA HGVDKVVACTSAFLLWDPTK VPPRLQAVTDDHIRMHKVLR ESGLKYVAVMPPHIGDQPLT GAYTVTLDGRGPSRVISKHD LGHFMLRCLTTDEYDGHSTY PSHQYQ
Tissue Specificity Predominantly expressed in liver and erythrocytes. At lower levels in heart, lung, adrenal gland and cerebrum.
Function Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.
Protein Name Flavin Reductase
Nadph
Fr
Biliverdin Reductase B
Bvr-B
Biliverdin-Ix Beta-Reductase
Green Heme-Binding Protein
Ghbp
Nadph-Dependent Diaphorase
Nadph-Flavin Reductase
Flr
Database Links Reactome: R-HSA-189483
Reactome: R-HSA-9707564
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Flavin Reductase antibody
Anti-Nadph antibody
Anti-Fr antibody
Anti-Biliverdin Reductase B antibody
Anti-Bvr-B antibody
Anti-Biliverdin-Ix Beta-Reductase antibody
Anti-Green Heme-Binding Protein antibody
Anti-Ghbp antibody
Anti-Nadph-Dependent Diaphorase antibody
Anti-Nadph-Flavin Reductase antibody
Anti-Flr antibody
Anti-BLVRB antibody
Anti-FLR antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance