Anti-Blood Group A-CD173 antibody [3-3A] (STJ16100981)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenA BALB/c mouse was immunized with mucin isolated from an ovarian cyst fluid (pure endocervical type according to the Fenoglio's classification). Fusion partner: SP2/0.
STJ16100981
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General Information

Short DescriptionMouse monoclonal antibody anti-Blood Group A-CD173 is suitable for use in Flow Cytometry, Immunofluorescence and Immunohistochemistry research applications.
ApplicationsFC/IF/IHC
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone ID3-3A
IsotypeIgG1k
ConjugationUnconjugated
ConcentrationCan be provided as 100 ยตg/mL, 500 ยตg/mL or 1mg/mL.
PurificationAffinity purified from tissue culture.
Dilution RangeFlow Cytometry (0, 5 โ€“ 1, 0 ยตg/million cells in 0, 1 ml). Immunofluorescence (0, 5 โ€“ 1, 0 ยตg/ml). Immunohistology (formalin-fixed: 1-2 ยตg/ml for30 min at RT; requires boiling tissue sections in 10mM Citrate Buffer, pH 6, 0, for 10-20 min followed by
FormulationPBS with 0.02% Sodium Azide.
Storage InstructionStore for up to 1 year at 2-8ยฐC upon receipt.

Target Information

ImmunogenA BALB/c mouse was immunized with mucin isolated from an ovarian cyst fluid (pure endocervical type according to the Fenoglio's classification). Fusion partner: SP2/0.

Additional Info

Background 3-3A reacts with determinants of chain A type 3 and 4 and chain H type 3 and 4, but not with type 1 and 2 chain structures. It is not reactive with immunodominant A trisaccharide. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas. 3-3A does not react with normal tissue sections of donors with blood group B and 0 but it reacts specifically with malignant tissues in these individuals.

Information sourced from Uniprot.org

Citations

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