Anti-Blood Group A-CD173 antibody [3-3A] (STJ16100981)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenA BALB/c mouse was immunized with mucin isolated from an ovarian cyst fluid (pure endocervical type according to the Fenoglio's classification). Fusion partner: SP2/0.
General Information
| Short Description | Mouse monoclonal antibody anti-Blood Group A-CD173 is suitable for use in Flow Cytometry, Immunofluorescence and Immunohistochemistry research applications. |
| Applications | FC/IF/IHC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 3-3A |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | Can be provided as 100 ยตg/mL, 500 ยตg/mL or 1mg/mL. |
| Purification | Affinity purified from tissue culture. |
| Dilution Range | Flow Cytometry (0, 5 โ 1, 0 ยตg/million cells in 0, 1 ml). Immunofluorescence (0, 5 โ 1, 0 ยตg/ml). Immunohistology (formalin-fixed: 1-2 ยตg/ml for30 min at RT; requires boiling tissue sections in 10mM Citrate Buffer, pH 6, 0, for 10-20 min followed by |
| Formulation | PBS with 0.02% Sodium Azide. |
| Storage Instruction | Store for up to 1 year at 2-8ยฐC upon receipt. |
Target Information
| Immunogen | A BALB/c mouse was immunized with mucin isolated from an ovarian cyst fluid (pure endocervical type according to the Fenoglio's classification). Fusion partner: SP2/0. |
Additional Info
| Background | 3-3A reacts with determinants of chain A type 3 and 4 and chain H type 3 and 4, but not with type 1 and 2 chain structures. It is not reactive with immunodominant A trisaccharide. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas. 3-3A does not react with normal tissue sections of donors with blood group B and 0 but it reacts specifically with malignant tissues in these individuals. |
Information sourced from Uniprot.org