Anti-BKbeta2 K+ channel antibody [N53/32] (STJA0021565)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Calcium-Activated Potassium Channel Subunit Beta-2 antibody for use in IHC and WB in samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | N53/32 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | KCNMB2 |
| Gene ID | 10242 |
| Uniprot ID | KCMB2_HUMAN |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons. |
| Protein Name | Calcium-Activated Potassium Channel Subunit Beta-2Bk Channel Subunit Beta-2Bkbeta2Hbeta2Calcium-Activated Potassium Channel - Subfamily M Subunit Beta-2Charybdotoxin Receptor Subunit Beta-2Hbeta3K(Vcabeta-2Maxi K Channel Subunit Beta-2Slo-Beta-2 |
| Database Links | Reactome: R-HSA-1296052Reactome: R-HSA-418457 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Calcium-Activated Potassium Channel Subunit Beta-2 antibodyAnti-Bk Channel Subunit Beta-2 antibodyAnti-Bkbeta2 antibodyAnti-Hbeta2 antibodyAnti-Calcium-Activated Potassium Channel - Subfamily M Subunit Beta-2 antibodyAnti-Charybdotoxin Receptor Subunit Beta-2 antibodyAnti-Hbeta3 antibodyAnti-K(Vcabeta-2 antibodyAnti-Maxi K Channel Subunit Beta-2 antibodyAnti-Slo-Beta-2 antibodyAnti-KCNMB2 antibody |
Information sourced from Uniprot.org