Anti-Bisphosphate 3 NA-nucleotidase antibody (C-Term) (STJ71287)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Bisphosphate 3 nucleotidase (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 37kDa band observed in Human Liver lysates (calculated MW of 33.4kDa according to NP_006076.4). The observed molecular weight corresponds to earlier findings in literature with d |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | BPNT1 |
| Gene ID | 10380 |
| Uniprot ID | BPNT1_HUMAN |
| Accession Number | NP_006076.4 |
| Immunogen Region | C-Term |
| Immunogen Sequence | RNYDYYASRVPESIK |
Additional Info
| Function | Phosphatase that converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP and inositol 1,4-bisphosphate (Ins(1,4)P2) to inositol 4-phosphate. Is also able to hydrolyze adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS). Probably prevents the toxic accumulation of PAP, a compound which inhibits a variety of proteins, including PAPS-utilizing enzymes such as sulfotransferases, and RNA processing enzymes. Could also play a role in inositol recycling and phosphoinositide metabolism. Is not active on 3'-AMP, inositol-1-phosphate and inositol-1,4,5-triphosphate. |
| Protein Name | 3'(2' -5'-Bisphosphate Nucleotidase 13'-Phosphoadenosine 5'-Phosphate PhosphatasePap PhosphataseBisphosphate 3'-Nucleotidase 1Bpntase 1HspipInositol-Polyphosphate 1-Phosphatase |
| Database Links | Reactome: R-HSA-156584 |
| Alternative Antibody Names | Anti-3'(2' -5'-Bisphosphate Nucleotidase 1 antibodyAnti-3'-Phosphoadenosine 5'-Phosphate Phosphatase antibodyAnti-Pap Phosphatase antibodyAnti-Bisphosphate 3'-Nucleotidase 1 antibodyAnti-Bpntase 1 antibodyAnti-Hspip antibodyAnti-Inositol-Polyphosphate 1-Phosphatase antibodyAnti-BPNT1 antibody |
Information sourced from Uniprot.org