Anti-BHMT antibody (1-406aa) [3D6] (STJA0041957)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenRecombinant human BHMT (1-406aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-BHMT (1-406aa) for use in ELISA, WB, ICC, IF and FACS in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF/FACS |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 3D6 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BHMT |
| Gene ID | 635 |
| Uniprot ID | BHMT1_HUMAN |
| Accession Number | NP_001704 |
| Immunogen | Recombinant human BHMT (1-406aa) purified from E. coli |
| Immunogen Region | 1-406aa |
Additional Info
| Tissue Specificity | Found exclusively in liver and kidney. |
| Function | Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. |
| Protein Name | Betaine--Homocysteine S-Methyltransferase 1 |
| Database Links | Reactome: R-HSA-1614635Reactome: R-HSA-6798163 |
| Cellular Localisation | CytoplasmCytosolNucleusPredominantly Localized In The Cytoplasm With A Small Fraction Detected In The NucleusTranslocates Into The Nucleus Upon Oxidative Stress |
| Alternative Antibody Names | Anti-Betaine--Homocysteine S-Methyltransferase 1 antibodyAnti-BHMT antibody |
Information sourced from Uniprot.org