| Function | Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'. |
| Protein Name | Class A Basic Helix-Loop-Helix Protein 15Bhlha15Class B Basic Helix-Loop-Helix Protein 8Bhlhb8Muscle - Intestine And Stomach Expression 1Mist-1 |
| Database Links | Reactome: R-HSA-9925561 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Class A Basic Helix-Loop-Helix Protein 15 antibodyAnti-Bhlha15 antibodyAnti-Class B Basic Helix-Loop-Helix Protein 8 antibodyAnti-Bhlhb8 antibodyAnti-Muscle - Intestine And Stomach Expression 1 antibodyAnti-Mist-1 antibodyAnti-BHLHA15 antibodyAnti-BHLHB8 antibodyAnti-MIST1 antibody |
Information sourced from Uniprot.org
