Anti-BHLHA15 antibody (STJA0008892)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human BHLHA15
General Information
| Short Description | Rabbit polyclonal anti-Class A basic helix-loop-helix protein 15 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BHLHA15 |
| Gene ID | 168620 |
| Uniprot ID | BHA15_HUMAN |
| Immunogen | Synthesized peptide derived from human BHLHA15 |
| Specificity | This antibody detects endogenous levels of BHLHA15 at Human, Mouse, Rat |
Additional Info
| Function | Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'. |
| Protein Name | Class A Basic Helix-Loop-Helix Protein 15Bhlha15Class B Basic Helix-Loop-Helix Protein 8Bhlhb8Muscle - Intestine And Stomach Expression 1Mist-1 |
| Database Links | Reactome: R-HSA-9925561 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Class A Basic Helix-Loop-Helix Protein 15 antibodyAnti-Bhlha15 antibodyAnti-Class B Basic Helix-Loop-Helix Protein 8 antibodyAnti-Bhlhb8 antibodyAnti-Muscle - Intestine And Stomach Expression 1 antibodyAnti-Mist-1 antibodyAnti-BHLHA15 antibodyAnti-BHLHB8 antibodyAnti-MIST1 antibody |
Information sourced from Uniprot.org