Anti-BGN antibody (38-368) (STJ28337)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal BGN (38-368) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BGN |
| Gene ID | 633 |
| Uniprot ID | PGS1_HUMAN |
| Immunogen Region | 38-368 |
| Immunogen Sequence | DEEASGADTSGVLDPDSVTP TYSAMCPFGCHCHLRVVQCS DLGLKSVPKEISPDTTLLDL QNNDISELRKDDFKGLQHLY ALVLVNNKISKIHEKAFSPL RKLQKLYISKNHLVEIPPNL PSSLVELRIHDNRIRKVPKG VFSGLRNMNCIEMGGNPLEN SGFEPGAFDGLKLNYLRISE AKLTGIPKDLPETLNELHLD HNKIQAIELEDLLRYSKLYR LGLGHNQIRMIENGSLSFL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 38-368 of human BGN (NP_001702.1). |
Additional Info
| Tissue Specificity | Detected in placenta (at protein level). Found in several connective tissues, especially in articular cartilages. |
| Post Translational Modifications | The two attached glycosaminoglycan chains can be either chondroitin sulfate or dermatan sulfate. |
| Function | May be involved in collagen fiber assembly. |
| Protein Name | BiglycanBone/Cartilage Proteoglycan IPg-S1 |
| Database Links | Reactome: R-HSA-1971475Reactome: R-HSA-2022870Reactome: R-HSA-2022923Reactome: R-HSA-2024101Reactome: R-HSA-3000178Reactome: R-HSA-3560783Reactome: R-HSA-3560801Reactome: R-HSA-3595172Reactome: R-HSA-3595174Reactome: R-HSA-3595177Reactome: R-HSA-4420332 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Biglycan antibodyAnti-Bone/Cartilage Proteoglycan I antibodyAnti-Pg-S1 antibodyAnti-BGN antibodyAnti-SLRR1A antibody |
Information sourced from Uniprot.org