Anti-BGN antibody (20-230) (STJ116192)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ116192
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General Information

Short DescriptionRabbit polyclonal BGN (20-230) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolBGN
Gene ID633
Uniprot IDPGS1_HUMAN
Immunogen Region20-230
Immunogen SequenceEQRGFWDFTLDDGPFMMNDE EASGADTSGVLDPDSVTPTY SAMCPFGCHCHLRVVQCSDL GLKSVPKEISPDTTLLDLQN NDISELRKDDFKGLQHLYAL VLVNNKISKIHEKAFSPLRK LQKLYISKNHLVEIPPNLPS SLVELRIHDNRIRKVPKGVF SGLRNMNCIEMGGNPLENSG FEPGAFDGLKLNYLRISEAK LTGIPKDLPET
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 20-230 of human BGN (NP_001702.1).

Additional Info

Tissue Specificity Detected in placenta (at protein level). Found in several connective tissues, especially in articular cartilages.
Post Translational Modifications The two attached glycosaminoglycan chains can be either chondroitin sulfate or dermatan sulfate.
Function May be involved in collagen fiber assembly.
Protein Name Biglycan
Bone/Cartilage Proteoglycan I
Pg-S1
Database Links Reactome: R-HSA-1971475
Reactome: R-HSA-2022870
Reactome: R-HSA-2022923
Reactome: R-HSA-2024101
Reactome: R-HSA-3000178
Reactome: R-HSA-3560783
Reactome: R-HSA-3560801
Reactome: R-HSA-3595172
Reactome: R-HSA-3595174
Reactome: R-HSA-3595177
Reactome: R-HSA-4420332
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Biglycan antibody
Anti-Bone/Cartilage Proteoglycan I antibody
Anti-Pg-S1 antibody
Anti-BGN antibody
Anti-SLRR1A antibody

Information sourced from Uniprot.org

Citations

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