• Western blot analysis of various lysates using BGN Rabbit polyclonal antibody (STJ116192) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-BGN antibody (20-230) (STJ116192)

SKU:
STJ116192

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BGN (20-230) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BGN
Gene ID: 633
Uniprot ID: PGS1_HUMAN
Immunogen Region: 20-230
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-230 of human BGN (NP_001702.1).
Immunogen Sequence: EQRGFWDFTLDDGPFMMNDE EASGADTSGVLDPDSVTPTY SAMCPFGCHCHLRVVQCSDL GLKSVPKEISPDTTLLDLQN NDISELRKDDFKGLQHLYAL VLVNNKISKIHEKAFSPLRK LQKLYISKNHLVEIPPNLPS SLVELRIHDNRIRKVPKGVF SGLRNMNCIEMGGNPLENSG FEPGAFDGLKLNYLRISEAK LTGIPKDLPET
Tissue Specificity Detected in placenta (at protein level). Found in several connective tissues, especially in articular cartilages.
Post Translational Modifications The two attached glycosaminoglycan chains can be either chondroitin sulfate or dermatan sulfate.
Function May be involved in collagen fiber assembly.
Protein Name Biglycan
Bone/Cartilage Proteoglycan I
Pg-S1
Database Links Reactome: R-HSA-1971475
Reactome: R-HSA-2022870
Reactome: R-HSA-2022923
Reactome: R-HSA-2024101
Reactome: R-HSA-3000178
Reactome: R-HSA-3560783
Reactome: R-HSA-3560801
Reactome: R-HSA-3595172
Reactome: R-HSA-3595174
Reactome: R-HSA-3595177
Reactome: R-HSA-4420332
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Biglycan antibody
Anti-Bone/Cartilage Proteoglycan I antibody
Anti-Pg-S1 antibody
Anti-BGN antibody
Anti-SLRR1A antibody

Information sourced from Uniprot.org

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