| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BFAR |
| Gene ID: | 51283 |
| Uniprot ID: | BFAR_HUMAN |
| Immunogen Region: | 1-140 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human BFAR (NP_057645.1). |
| Immunogen Sequence: | MEEPQKSYVNTMDLERDEPL KSTGPQISVSEFSCHCCYDI LVNPTTLNCGHSFCRHCLAL WWASSKKTECPECREKWEGF PKVSILLRDAIEKLFPDAIR LRFEDIQQNNDIVQSLAAFQ KYGNDQIPLAPNTGRANQQM |
| Tissue Specificity | Expressed highly in brain, moderately in small intestine, weakly in testes and only faintly in liver and skeletal muscle. Not expressed in heart, kidney, lung and spleen. |
| Function | Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors. |
| Protein Name | Bifunctional Apoptosis RegulatorRing Finger Protein 47 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Bifunctional Apoptosis Regulator antibodyAnti-Ring Finger Protein 47 antibodyAnti-BFAR antibodyAnti-BAR antibodyAnti-RNF47 antibody |
Information sourced from Uniprot.org