Anti-BEX3 antibody (STJ13100725)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from human Brain-expressed X-linked protein 3 (BEX3, NGFRAP1, NADE) conjugated to an immunogenic carrier protein was used as the immunogen.
General Information
| Short Description | Rabbit polyclonal anti-BEX3 for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | BEX3 |
| Gene ID | 27018 |
| Uniprot ID | BEX3_HUMAN |
| Immunogen | A synthetic peptide from human Brain-expressed X-linked protein 3 (BEX3, NGFRAP1, NADE) conjugated to an immunogenic carrier protein was used as the immunogen. |
| Specificity | Specific for BEX3. |
Additional Info
| Post Translational Modifications | Ubiquitinated. Degraded by the proteasome. |
| Function | May be a signaling adapter molecule involved in NGFR/p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. In absence of reductive stress, acts as a pseudosubstrate for the CRL2(FEM1B) complex: associates with FEM1B via zinc, thereby preventing association between FEM1B and its substrates. |
| Protein Name | Protein Bex3Brain-Expressed X-Linked Protein 3Nerve Growth Factor Receptor-Associated Protein 1Ovarian Granulosa Cell 13.0 Kda Protein Hgr74P75ntr-Associated Cell Death Executor |
| Database Links | Reactome: R-HSA-205025 |
| Cellular Localisation | NucleusCytoplasmCytosolShuttles Between The Cytoplasm And The NucleusAssociates With Replicating Mitochondria |
| Alternative Antibody Names | Anti-Protein Bex3 antibodyAnti-Brain-Expressed X-Linked Protein 3 antibodyAnti-Nerve Growth Factor Receptor-Associated Protein 1 antibodyAnti-Ovarian Granulosa Cell 13.0 Kda Protein Hgr74 antibodyAnti-P75ntr-Associated Cell Death Executor antibodyAnti-BEX3 antibodyAnti-DXS6984E antibodyAnti-NADE antibodyAnti-NGFRAP1 antibody |
Information sourced from Uniprot.org