Anti-Beta-2 microglobulin antibody [EBS-O-109] (STJ16101034)

Name: Anti-Beta-2 microglobulin antibody [EBS-O-109] (STJ16101034)
SKU: STJ16101034
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostMouse

ConjugationUnconjugated

IsotypeIgG2ak

ImmunogenA BALB/c mouse was immunized with human PBL from a T-ALL patient. Fusion partner: NS-1.

STJ16101034

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Short Description	Mouse monoclonal anti-Beta-2 microglobulin for use in ELISA, FC and IHC in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	ELISA/FC/IHC
Host	Mouse
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	EBS-O-109
Isotype	IgG2ak
Conjugation	Unconjugated
Concentration	Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Purification	Affinity purified from tissue culture.
Dilution Range	ELISA (solid phase: 0, 1-100 µg/ml; tracer: 0, 001-100 µg/ml for 30 min at RT). Flow cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Immunohistology (1-2 µg/ml for 30-60 minutes at RT; information on a suitable antigen retrieval method for stainin
Formulation	PBS with 0.02% Sodium Azide.
Storage Instruction	Store for up to 1 year at 2-8°C upon receipt.

Gene Symbol	B2M
Gene ID	567
Uniprot ID	B2MG_HUMAN
Immunogen	A BALB/c mouse was immunized with human PBL from a T-ALL patient. Fusion partner: NS-1.

Post Translational Modifications	Glycation of Ile-21 is observed in long-term hemodialysis patients.
Function	Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.
Protein Name	Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3
Database Links	Reactome: R-HSA-1236974 Reactome: R-HSA-1236977 Reactome: R-HSA-164940 Reactome: R-HSA-198933 Reactome: R-HSA-2172127 Reactome: R-HSA-2424491 Reactome: R-HSA-6798695 Reactome: R-HSA-877300 Reactome: R-HSA-9637628 Reactome: R-HSA-9705671 Reactome: R-HSA-977225 Reactome: R-HSA-983170
Cellular Localisation	Secreted Cell Surface Detected In Serum And Urine (Microbial Infection) In The Presence Of M Tuberculosis Esxa-Esxb Complex Decreased Amounts Of B2m Are Found On The Cell Surface
Alternative Antibody Names	Anti-Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3 antibody Anti-B2M antibody Anti-CDABP0092 antibody Anti-HDCMA22P antibody

Information sourced from Uniprot.org