Anti-BEST3 antibody (C-Term) {FITC} (STJ500248)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationFITC
IsotypeIgG
ImmunogenSynthetic peptide taken within the last 50 amino acids from the C-terminus of rat Bestrophin-3 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-BEST3 (C-Term) is suitable for use in Confocal Microscopy, ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications | CM/ELISA/IF/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | FITC |
| Concentration | 0.5 µg/µl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500-1:1, 000DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:200ICC: 1:200IF: 1:200CFM: 1:200 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Best3 |
| Gene ID | 382427 |
| Uniprot ID | BEST3_MOUSE |
| Immunogen | Synthetic peptide taken within the last 50 amino acids from the C-terminus of rat Bestrophin-3 protein. |
| Immunogen Region | C-Term |
Additional Info
| Tissue Specificity | Isoform 1: Expressed in heart. Isoform 2: Expressed in brain, retina/retinal pigment epithelium (RPE) and skeletal muscle. Expressed in acinar cells of parotid glands. Expressed in lung, kidney and testis. |
| Function | Isoform 1: Ligand-gated anion channel that allows the movement of chloride monoatomic anions across cell membranes when activated by calcium (Ca2+). Isoform 2: Does not function as calcium-gated chloride channel. |
| Protein Name | Bestrophin-3Vitelliform Macular Dystrophy 2-Like Protein 3 |
| Database Links | Reactome: R-MMU-2672351 |
| Cellular Localisation | Isoform 1: Cell MembraneLocalized Also In Punctate Structures In The Cytosolic CompartmentIsoform 2: Cell Membrane |
| Alternative Antibody Names | Anti-Bestrophin-3 antibodyAnti-Vitelliform Macular Dystrophy 2-Like Protein 3 antibodyAnti-Best3 antibodyAnti-Vmd2l3 antibody |
Information sourced from Uniprot.org