• Immunohistochemistry of mouse tissue with Anti-BEST1 primary antibody (STJ500233) at 1:50 dilution in Buffer. Section was treated with DAB and Haematoxylin stain. Magnification is at 40X.

Anti-BEST1 antibody (500-585) (STJ500233)

SKU:
STJ500233-100

€601.88
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Host: Rabbit
Applications: CM/ELISA/IF/IHC/IP/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BEST1 (500-585) is suitable for use in Confocal Microscopy, ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.75 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:100
ICC: 1:100
IF: 1:100
CFM: 1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: BEST1
Gene ID: 7439
Uniprot ID: BEST1_HUMAN
Immunogen Region: 500-585
Specificity: This peptide will label the Bestrophin 1-1-2,-3,-4,-5 isoforms that are produced by alternate splicing of the C-terminal end.
Immunogen: Synthetic peptide taken within amino acid region 500-585 on human Bestrophin-1 isoform 1 protein.
Tissue Specificity Predominantly expressed in the basolateral membrane of the retinal pigment epithelium.
Post Translational Modifications Phosphorylated by PP2A.
Function Forms calcium-sensitive chloride channels. Highly permeable to bicarbonate.
Protein Name Bestrophin-1
Tu15b
Vitelliform Macular Dystrophy Protein 2
Database Links Reactome: R-HSA-2672351
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Basolateral Cell Membrane
Alternative Antibody Names Anti-Bestrophin-1 antibody
Anti-Tu15b antibody
Anti-Vitelliform Macular Dystrophy Protein 2 antibody
Anti-BEST1 antibody
Anti-VMD2 antibody

Information sourced from Uniprot.org

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