Anti-BDH2/DHRS6 antibody (92-103) (STJ71470)

SKU:
STJ71470-100

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Host: Goat
Applications: Pep-ELISA
Reactivity: Human/Mouse/Rat/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-BDH2/DHRS6 (92-103) is suitable for use in ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: ELISA-antibody detection limit dilution 1:128000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: BDH2
Gene ID: 56898
Uniprot ID: DHRS6_HUMAN
Immunogen Region: 92-103
Accession Number: NP_064524.3
Immunogen Sequence: DCEEKDWDFSMN
Function NAD(H)-dependent dehydrogenase/reductase with a preference for cyclic substrates. Catalyzes stereoselective conversion of 4-oxo-L-proline to cis-4-hydroxy-L-proline, likely a detoxification mechanism for ketoprolines. Mediates the formation of 2,5-dihydroxybenzoate (2,5-DHBA), a siderophore that chelates free cytoplasmic iron and associates with LCN2, thereby regulating iron transport and homeostasis while protecting cells against free radical-induced oxidative stress. The iron-siderophore complex is imported into mitochondria, providing an iron source for mitochondrial metabolic processes in particular heme synthesis. May act as a 3-hydroxybutyrate dehydrogenase.
Protein Name Dehydrogenase/Reductase Sdr Family Member 6
(R-Beta-Hydroxybutyrate Dehydrogenase
3-Hydroxybutyrate Dehydrogenase Type 2
4-Oxo-L-Proline Reductase
Oxidoreductase Ucpa
Short Chain Dehydrogenase/Reductase Family 15c Member 1
Database Links Reactome: R-HSA-77111
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Dehydrogenase/Reductase Sdr Family Member 6 antibody
Anti-(R-Beta-Hydroxybutyrate Dehydrogenase antibody
Anti-3-Hydroxybutyrate Dehydrogenase Type 2 antibody
Anti-4-Oxo-L-Proline Reductase antibody
Anti-Oxidoreductase Ucpa antibody
Anti-Short Chain Dehydrogenase/Reductase Family 15c Member 1 antibody
Anti-BDH2 antibody
Anti-DHRS6 antibody
Anti-SDR15C1 antibody
Anti-UNQ6308 antibody
Anti-PRO20933 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance