Anti-BCMO1 antibody (268-547) (STJ118293)

Name: Anti-BCMO1 antibody (268-547) (STJ118293)
SKU: STJ118293
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ118293

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Short Description	Rabbit polyclonal BCMO1 (268-547) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	BCO1
Gene ID	53630
Uniprot ID	BCDO1_HUMAN
Immunogen Region	268-547
Immunogen Sequence	MSWASCLAFHREEKTYIHII DQRTRQPVQTKFYTDAMVVF HHVNAYEEDGCIVFDVIAYE DNSLYQLFYLANLNQDFKEN SRLTSVPTLRRFAVPLHVDK NAEVGTNLIKVASTTATALK EEDGQVYCQPEFLYEGLELP RVNYAHNGKQYRYVFATGVQ WSPIPTKIIKYDILTKSSLK WREDDCWPAEPLFVPAPGAK DEDDGVILSAIVSTDPQKLP FLLILDAKSFTELARASVD
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 268-547 of human BCMO1 (NP_059125.2).

Tissue Specificity	Highly expressed in retinal pigment epithelium. Also expressed in kidney, testis, liver, brain, small intestine and colon.
Function	Symmetrically cleaves beta-carotene into two molecules of retinal using a dioxygenase mechanism.
Protein Name	Beta -Beta-Carotene 15 -15'-Dioxygenase Beta-Carotene Dioxygenase 1 Beta-Carotene Oxygenase 1
Database Links	Reactome: R-HSA-975634
Cellular Localisation	Cytoplasm Cytosol
Alternative Antibody Names	Anti-Beta -Beta-Carotene 15 -15'-Dioxygenase antibody Anti-Beta-Carotene Dioxygenase 1 antibody Anti-Beta-Carotene Oxygenase 1 antibody Anti-BCO1 antibody Anti-BCDO antibody Anti-BCDO1 antibody Anti-BCMO1 antibody

Information sourced from Uniprot.org