Anti-BCL2L14 antibody (1-327) (STJ28561)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal BCL2L14 (1-327) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:10-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BCL2L14 |
| Gene ID | 79370 |
| Uniprot ID | B2L14_HUMAN |
| Immunogen Region | 1-327 |
| Immunogen Sequence | MCSTSGCDLEEIPLDDDDLN TIEFKILAYYTRHHVFKSTP ALFSPKLLRTRSLSQRGLGN CSANESWTEVSWPCRNSQSS EKAINLGKKKSSWKAFFGVV EKEDSQSTPAKVSAQGQRTL EYQDSHSQQWSRCLSNVEQC LEHEAVDPKVISIANRVAEI VYSWPPPQATQAGGFKSKEI FVTEGLSFQLQGHVPVASSS KKDEEEQILAKIVELLKYSG DQLERKLKKDKALMGHFQD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-327 of human BCL2L14/BCLG (NP_620049.1). |
Additional Info
| Tissue Specificity | Isoform 1 is widely expressed. Isoform 2 is testis-specific. |
| Post Translational Modifications | Phosphorylated by MELK, leading to inhibit its pro-apoptotic function. |
| Function | Plays a role in apoptosis. |
| Protein Name | Apoptosis Facilitator Bcl-2-Like Protein 14Bcl2-L-14Apoptosis Regulator Bcl-G |
| Database Links | Reactome: R-HSA-6803205 |
| Cellular Localisation | CytoplasmIsoform 1: CytoplasmCytosolDiffusely Distributed Throughout The CytosolIsoform 2: Endomembrane SystemPredominantly Localized To Cytosolic Organelles |
| Alternative Antibody Names | Anti-Apoptosis Facilitator Bcl-2-Like Protein 14 antibodyAnti-Bcl2-L-14 antibodyAnti-Apoptosis Regulator Bcl-G antibodyAnti-BCL2L14 antibodyAnti-BCLG antibody |
Information sourced from Uniprot.org