| Short Description : | Rabbit polyclonal Bcl-2-Related Protein A1 (70-150) antibody for use in WB, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BCL2A1 |
| Gene ID: | 597 |
| Uniprot ID: | B2LA1_HUMAN |
| Immunogen Region: | 70-150 |
| Immunogen Sequence: | LFNQVMEKEFEDGIINWGRI VTIFAFEGILIKKLLRQQIA PDVDTYKEISYFVAEFIMNN TGEWIRQNGGWENGFVKKFE P |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 70-150 of human BCL2A1 (NP_004040.1). |
| Tissue Specificity | Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies. |
| Function | Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection. Can inhibit apoptosis induced by serum starvation in the mammary epithelial cell line HC11. |
| Protein Name | Bcl-2-Related Protein A1Bcl-2-Like Protein 5Bcl2-L-5Hemopoietic-Specific Early Response ProteinProtein Bfl-1Protein Grs |
| Database Links | Reactome: R-HSA-9725371Reactome: R-HSA-9824594 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Bcl-2-Related Protein A1 antibodyAnti-Bcl-2-Like Protein 5 antibodyAnti-Bcl2-L-5 antibodyAnti-Hemopoietic-Specific Early Response Protein antibodyAnti-Protein Bfl-1 antibodyAnti-Protein Grs antibodyAnti-BCL2A1 antibodyAnti-BCL2L5 antibodyAnti-BFL1 antibodyAnti-GRS antibodyAnti-HBPA1 antibody |
Information sourced from Uniprot.org
