![Anti-Bcl-6 Oncoprotein antibody [LN22] (STJ16101682)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/152188/347040/STJ16101682_1__28412.1681999296.jpg?c=1 "Anti-Bcl-6 Oncoprotein antibody [LN22] (STJ16101682)")
![Anti-Bcl-6 Oncoprotein antibody [LN22] (STJ16101682)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/152188/347040/STJ16101682_1__28412.1681999296.jpg?c=1 "Anti-Bcl-6 Oncoprotein antibody [LN22] (STJ16101682)")
Anti-Bcl-6 Oncoprotein antibody [LN22] (STJ16101682)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2b
ImmunogenProkaryotic recombinant protein containing 1–350 amino acids of the N-terminus of the Bcl-6 human oncoprotein molecule.
General Information
| Short Description | Mouse monoclonal anti-Bcl-6 Oncoprotein for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | LN22 |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Concentration | >=220 mg/L |
| Dilution Range | IHC-P 1:60 |
| Formulation | Tissue culture supernatant with sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | Prokaryotic recombinant protein containing 1–350 amino acids of the N-terminus of the Bcl-6 human oncoprotein molecule. |
Additional Info
| Background | Bcl-6 is a proto-oncogene that encodes a Kruppel-type zinc-finger protein of 95 kD and shares homology with other transcription factors. Bcl-6 protein is mainly expressed in normal germinal center B cells and related lymphomas. It has been shown that the Bcl-6 proto-oncogene is involved in chromosome rearrangements at 3q27 in non-Hodgkin s lymphomas and Bcl-6 rearrangements have also been detected in 33-45% of diffuse large B cell lymphomas. Immunohistochemistry has been reported to show the Bcl-6 gene product to be detectable in follicular lymphomas, diffuse large B cell lymphomas, Burkitt s lymphomas and in nodular, lymphocyte predominant Hodgkin s disease. |
Information sourced from Uniprot.org