• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-BCE1 antibody (11-61 aa) (STJ196617)

SKU:
STJ196617

$62.10 - $305.10
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Putative protein BCE-1 (11-61 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BCE1Uniprot ID=BCE1_HUMAN"
Immunogen Region: 11-61 aa
Specificity: This antibody detects endogenous levels of BCE1 at Human
Immunogen: Synthesized peptide derived from the human BCE1 at the amino acid range 11-61
Post Translational Modifications Phosphorylated. PAX5 binding increases phosphorylation. Ubiquitinated by XIAP/BIRC4.
Function Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression.
Protein Name Transducin-Like Enhancer Protein 4
Grg-4
Groucho-Related Protein 4
Database Links Reactome: R-HSA-201722
Reactome: R-HSA-2122947
Reactome: R-HSA-3769402
Reactome: R-HSA-4641265
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Transducin-Like Enhancer Protein 4 antibody
Anti-Grg-4 antibody
Anti-Groucho-Related Protein 4 antibody
Anti-TLE4 antibody
Anti-GRG4 antibody
Anti-KIAA1261 antibody

Information sourced from Uniprot.org

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