Anti-BCAS2 antibody (176-225 aa) (STJ91829)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human BCAS2 at the amino acid range 176-225
General Information
| Short Description | Rabbit polyclonal anti-Pre-mRNA-splicing factor SPF27 (176-225 aa) for use in WB and ELISA in Human, Mouse, Rat and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:5000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BCAS2 |
| Gene ID | 10286 |
| Uniprot ID | SPF27_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human BCAS2 at the amino acid range 176-225 |
| Immunogen Region | 176-225 aa |
| Specificity | BCAS2 Polyclonal Antibody detects endogenous levels of BCAS2 protein. |
Additional Info
| Function | Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). |
| Protein Name | Pre-Mrna-Splicing Factor Spf27Breast Carcinoma-Amplified Sequence 2Dna Amplified In Mammary Carcinoma 1 ProteinSpliceosome-Associated Protein Spf 27 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Pre-Mrna-Splicing Factor Spf27 antibodyAnti-Breast Carcinoma-Amplified Sequence 2 antibodyAnti-Dna Amplified In Mammary Carcinoma 1 Protein antibodyAnti-Spliceosome-Associated Protein Spf 27 antibodyAnti-BCAS2 antibodyAnti-DAM1 antibody |
Information sourced from Uniprot.org