| Host: |
Rabbit |
| Applications: |
WB/IHC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-BCAS2 (1-225) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
BCAS2 |
| Gene ID: |
10286 |
| Uniprot ID: |
SPF27_HUMAN |
| Immunogen Region: |
1-225 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human BCAS2 (NP_005863.1). |
| Immunogen Sequence: |
MAGTGLVAGEVVVDALPYFD QGYEAPGVREAAAALVEEET RRYRPTKNYLSYLTAPDYSA FETDIMRNEFERLAARQPIE LLSMKRYELPAPSSGQKNDI TAWQECVNNSMAQLEHQAVR IENLELMSQHGCNAWKVYNE NLVHMIEHAQKELQKLRKHI QDLNWQRKNMQLTAGSKLRE MESNWVSLVSKNYEIERTIV QLENEIYQIKQQHGEANKEN IRQDF |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). |
| Protein Name | Pre-Mrna-Splicing Factor Spf27Breast Carcinoma-Amplified Sequence 2Dna Amplified In Mammary Carcinoma 1 ProteinSpliceosome-Associated Protein Spf 27 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Pre-Mrna-Splicing Factor Spf27 antibodyAnti-Breast Carcinoma-Amplified Sequence 2 antibodyAnti-Dna Amplified In Mammary Carcinoma 1 Protein antibodyAnti-Spliceosome-Associated Protein Spf 27 antibodyAnti-BCAS2 antibodyAnti-DAM1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and Catalasealase knockout (KO) HeLa cells, using [KO Validated] Catalase Rabbit polyclonal antibody (STJ119991) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98776/382824/STJ119991_1__14020.1713151324.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and Catalasealase knockout (KO) HeLa cells, using [KO Validated] Catalase Rabbit polyclonal antibody (STJ119991) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.")
